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Note on humans: These benefits are not established in humans no completed human efficacy trials of MOTS-c exist [8]

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Reverse osmosis water and irradiated food (Picolab Rodent Diet 20, 5053) were supplied

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Testicular postgenomics: targeting the regulation of spermatogenesis

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10.1007/s00441-011-1227-1 [DOI] [PubMed] [Google Scholar] 57.Chapman, H

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No finished-drug approval, no active IND, and no FDA-registered human clinical trials as of April 2026

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It activates amylin receptor pathways involved in satiety and energy balance regulation

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