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discovered, through experimental studies, that the expression of NADPH oxidase 4 (Nox4) was upregulated while the expression of Nrf2/HO-1 was downregulated in the hippocampus of diabetic rats (48)

On the other hand, glutathione acts as the bodys primary antioxidant defence system

Exp Biol Med (Maywood) (2011) 236:50514

The frequency of glutathione IV therapy depends on individual health goals and conditions

10.2147/ndt.S243551 22 LuY.CuiX.ZhangL.WangX.XuY.QinZ.et al (2022)

12 Cellular swelling, karyolysis, karyorrhexis, vacuolization, inflammation and release of cellular contents (alanine aminotransferase, ALT) are key processes of hepatocyte necrosis and related death in humans, as shown by the biochemical evidence of severe elevations in aminotransferases, especially ALT