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This type of BIM protein promotes drug resistance in NSCLC (non-small cell lung cancer) and CML (chronic myeloid leukemia) against tyrosine kinase inhibitors such as gefitinib and imatinib [67]

He calls this intelligence-infested matter computronium, which is matter and energy organized at optimum level for computation

Taketa T, Sudo K, Correa AM, Wadhwa R, Shiozaki H, Elimova E, Campagna MC, Blum MA, Skinner HD, Komaki RU, Lee JH, Bhutani MS, Weston BR, Rice DC , Swisher SG, Maru DM, Hofstetter WL, Ajani JA

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Further, sam2 -deficiency results in 50% more PM condition growth differences and approximately 6.5 times as many DEGs, demonstrating that its loss has greater cellular impacts, some of which are through decreased AdoMet concentration