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Glutathione-bound Mercury(II) triggers the catalytic depletion of the cellular GSH pool by a catalytic mechanism, which involves the presence of Mercury as the glutathione conjugate

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Each step is a little "upgrade" toward the active form which is part of why Retinol is gentler than prescription Retinoic Acid

Yenihayat F, zkan B, Kasap M et al (2018) Vitreous IL-8 and VEGF levels in diabetic macular edema with or without subretinal fluid

Anal Biochem, 2001, 295(1): 119-22

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