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NAC is routinely used in hospitals as an antidote to the pain reliever acetaminophen, particularly when ingested with alcohol, or taken in excessive amounts

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It is GPx4 that has the unique ability to reduce complex lipid hydroperoxides [128], which is beneficial, unless the enzyme is inactivated by elevated concentrations of peroxides or RCS itself [129]

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Wang et al., 2018)

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It plays a role in the protection of sperm membranes against the harmful effects of lipid peroxidation and/or in preventing the premature reaction of the acrosome [21]

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Neurochem Res 2003;28(9): 1339-1344

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Hyperglycemia and advanced glycation end products disrupt BBB and promote occludin and claudin-5 protein secretion on extracellular microvesicles

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