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10.1177/153537020422900206 8 AndersonM
Desagher S, Glowinski J, Premont J
When your internal systems are running efficiently, your skin often reflects that internal balance
Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression
Moreover, innate immune mediators such as IFN-, secreted by natural killer (NK) cells and innate lymphoid cells, can upregulate HLA class I expression on melanocytes, thereby amplifying CD8 + T cell recognition (75)
This is where the problem lies
