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PMID: 12374906 - review on peptides and ageing, covering the effects of pineal peptides on melatonin and gerontological parameters

Persaud SJ, Bewick GA (2014) Peptide YY: more than just an appetite regulator

Many drugs require continuous use and lose effectiveness over time

doi: 10.3390/ijms15034837

The gut-brain axis connection means that gut healing reduces systemic inflammation reaching the brain, while direct neurotransmitter effects address mood regulation centrally

Most community protocols use the intermittent approach because MOTS-c stays active in the AMPK pathway for roughly 72 hours per injection
