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Expression of this mutated gene greatly reduces expression and operation of astrocytic glutamate transporters, thus leading to an excitotoxicity linked to psychosocial abnormalities and impaired cognition

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Several cytokines, namely IL-12, -18, -21 and -27, were upregulated in tissue specimens from UC and CD patients, independent of inflammation, as non-inflamed tissue from those patients showed a similar increase in cytokine expression compared to healthy controls [70]

[DOI] [PubMed] [Google Scholar] 60.Wu Y, Whiteus C, Xu CS, Hayworth KJ, Weinberg RJ, Hess HF, et al

The group latencies for rats treated with aCSF aCSF were significantly shorter than the scopolamine treated group on day one of training