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Research suggests an observational association between low maternal B12 and impaired fetal neurodevelopment, though causality remains unproven

What is biologically interesting is not yet clinically justified In medicine, "biologically interesting" and "clinically justified" are not the same statement

By estimating the correlations between amplitudes of individual GH secretory events and the average acyl-ghrelin concentration in the 60-minute interval preceding each GH burst, the ghrelin/GH association was more than 3-fold lower in the older group compared with the young adults, thus suggesting that with normal aging, endogenous acyl-ghrelin levels are less tightly linked to GH regulation

10.1016/S0140-6736(19)31146-8 138

Think of it like this: peptides are large, carefully folded molecules

Masters KS, Shah DN, Leinwand LA, Anseth KS