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doi: 10.1007/s11033-022-07267-7

As an auxiliary method to HPLC, it improves the reliability of analytical results

Second, while the systemic (oral) route is the clinically adopted route of administration, it doesnt indicate the primary site of action of nicorandil

Mao Y, Zhang X, Zhang X, Lu G (2007) Development of an HPLC method for the determination of salidroside in beagle dog plasma after administration of salidroside injection: application to a pharmacokinetics study