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biomark Med

CBF measurements Mice were initially anesthetized with 3% isoflurane and maintained at 1.5% throughout the surgery

In assessing responses to metal stress, future research should exploit these systems to elucidate the output of the integrated GSH concept i.e

Reviewer 1 Building off of the last major Results comments, the Tam used in these studies influences cells that express ERT2 but likely has direct and indirect effects on other cells as well (as the authors know, since they have a nice ER discussion paragraph)

Rozenberg et al., 2017)

Atay SM, Correa AM, Hofstetter WL, Mehran RJ, Rice DC , Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh G, Antonoff MB