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25,26 Therefore, the cleaved complex is bacteriostatic rather than lethally damaging
Bojesen G
2020 Apr;16(2):169-176
Indeed, loss of GCH1, 6-pyruvoyl-tetrahydropterin synthase or sepiapterin reductase sensitize cancer cells to GPX4 inhibition [53] and overexpression of GCH1 is sufficient to increase resistance to Gpx4 loss and inhibition and imidazole ketone erastin (IKE) treatment [54]
Hetz C, Papa FR
Hn s dng: 3 nm k t ngy sn xut
