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Anemia ICD-10 to CPT and HCPCS Code Pairing: The Complete 2026 Reference The ICD-10 code submitted on an anemia claim must support the medical necessity of every CPT and HCPCS code billed alongside it

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3 Vitamin B12 deficiency The haematological effects of B12 deficiency are the same as for folate deficiency, and are characterised by macrocytic anaemia (with abnormally large red blood cells)