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Description
l-Arginine depletion blunts antitumor T-cell responses by inducing myeloid-derived suppressor cellssuppression of T-cell responses by L-arginine depletion

Bempedoic acid is a pro-drug that is converted exclusively in the liver to its active CoA-derivative, bempedoyl-CoA

Krauss, W.H

10.1111/bjd.13462 172

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Together, the alterations in cellular signaling pathways and the NF1+/ microenvironment promote cell survival and proliferation of MPNST (Figure 4)
