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Crit Rev Oncog 18(5):435448

Oncologist 23 , 849851 (2018)

Network analysis of human glaucomatous optic nerve head astrocytes
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ROS can also activate the mitogen-activated protein kinase (MAPK) signaling pathway and activator protein-1 (AP-1), thereby the upregulating matrix metalloproteinases (MMPs) and degrading matrix collagen [24]
