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doi: 10.1016/S1074-7613(00)80088-6 36 GregersenPKSilverJWinchesterRJ

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Im Vergleich zu den meisten anderen AHAs besitzt sie jedoch eine deutlich mildere peelende Wirkung

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In the cytosol/nucleus, SOD1, Prx1/2, GPx1/4 and the Grx/Trx1 systems, supported by abundant GSH, confine ROS and tune thiol switches on enzymes and transcriptional regulators while DNA repair machineries such as OGG1 and the base-excision repair (BER) pathway continuously survey and correct oxidative lesions, together establishing a compartment-aware redox homeostasis that enables signaling yet limits collateral damage (Le Gal et al

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11C 367

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& BRENDEL, M

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Probiotic and synbiotic trials in T2D and prediabetes report statistically significant reductions in fasting glucose, HbA 1 c and surrogate markers of oxidative stress, yet the absolute changes are limited and do not obviate the need for standard glucose-lowering therapy (Li G

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