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Salcaprozate sodium, or SNAC, is one of the most advanced intestinal permeation enhancers that have been tested in clinical trials for oral delivery of macromolecules

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To prevent it, wait a full 10 seconds after injecting before removing the needle

A provider-supervised taper or switch to oral B12 supplementation is a reasonable alternative if MIC B12 proves unsuitable

Pregnancy and nursing: No safety data exists
