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Rigorous human studies are required to determine safety parameters, mechanistic specificity, and potential translational relevance before any clinical applications can be considered

A serum B12 level below the normal expected range may indicate B12 deficiency [1]

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This allows toxins to be safely removed through bile or urine

Treasure Island (FL): StatPearls Publishing Copyright 2021, StatPearls Publishing LLC., 2021

For example, moderate concentrations of free fatty acids were found to augment GPx-1 activity in human ECV-304 and murine fibroblasts in a manner dependent on epidermal growth factor receptor (EGFR) activation (105)