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The reaction catalyzed by SHMT, which converts serine and tetrahydrofolate to glycine and 5,10-meTHF, is not only crucial for tumor cells but also essential for all rapidly proliferating normal cells [10]

Article ID 9450634

Pharmacologic and genetic manipulations of the cellular redox environment perturb normal cell-cycle progression [49,50]

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Explore literature discussions, model-system findings, and peptide research pathways
