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Recordkeeping: Log the daily dose, injection site and any observations to keep the protocol consistent

Twenty-five years after the publication of the first PROTAC, these are included within the Targeted Protein Degradation (TPD) field, which encompasses all innovative strategies aimed at chemically-induced protein degradation, known generically as degraders 26

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Consistent with our findings, PD-L1 regulation by AKT and MEK was also reported in other human tumor cell lines 28,29

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