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2001;280:E804815

Activated microglia can also induce astrocytes to transform into a neurotoxic A1 phenotype by secreting IL-1, C1q, and TNF [400]

Here, we synthesize multilevel links between insulin receptor signaling, intracellular stress modules (oxidative, endoplasmic reticulum, inflammatory, and fibrotic pathways), tissue-level dysfunction, and systemic inflammatory amplification

10.1523/JNEUROSCI.16-03-01066.1996 2 AlamM

Romiplostim dosing Recommended initial dose of romiplostim for adults and children with ITP Romiplostim 1 mcg/kg once weekly as a subcutaneous injection