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Higher baseline deficiency risk in the target population Research has consistently shown that individuals with obesity have higher rates of B12 deficiency compared to the general population
Even with the constant intermixing of the PM with endosomal compartments through vesicular transport involving membrane budding and fusion reactions, levels of PI(4,5)P 2 in endosomal membranes are remarkably low
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Liu J, Ames BN (2005) Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Alzheimers disease, and Parkinsons disease
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