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Importantly, decreased STAT-3 levels in NK cells were shown to enhance tumor surveillance by upregulating DNAX accessory molecule-1 (DNAM-1) expression

doi: 10.1080/10408398.2015.1046546 21

Perturbance of proinsulin folding is countered by the unfolded protein response (UPR)

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248 A small number of clinical studies have found that antioxidant vitamin E, CoQ10, and alpha-lipoic acid combined with polarized light are effective in controlling T2DM complications, including diabetic foot

Chalcone-induced dysregulation of Bcl-2 family proteins such as Bid, Bcl-xL, Mcl-1, Bad, and Bax significantly contributed to these processes, leading to caspase activation and PARP cleavage
