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The sensitivity of 18F-FDG PET to functional changes outside the striatum allows it to detect distinctive patterns of functional change in PD 27 , with greater utility for differential diagnosis from atypical Parkinsonism than dopaminergic PET 28
By inhibiting Gwt1, Fosmanogepix disrupts the anchoring of mannoproteins on the fungal surface, impairing growth and pathogenicity through a mechanism distinct from azoles and echinocandins, thereby reducing the likelihood of cross-resistance (Pappas et al., 2023)

Front Immunol 11:1120

Hu G, Cassano PA
