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Thus, LPF-35 emerges as a strong candidate for incorporation into next-generation bioactive dressings, aiming to accelerate wound repair while reducing local pain without the need for opioids or NSAIDs

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This activation leads to increased neutrophil activity and cytokine production (6)

mDNA-induced inflammatory responses were not dependent upon the hosts innate immune system, as mtDNA instillation in severe combined immune deficiency mice similarly resulted in profound lung inflammation and injury (Riley and Tait, 2020