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The oxidoreductase PYROXD1 uses NAD(P)(+) as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response

Oral administration is most preferred because of patient compliance and acceptability, but the physiological, enzymatic and chemical barriers for this route pose a significant challenge to the delivery of peptide and protein drugs

10.1016/j.freeradbiomed.2013.08.093 186 RumoraA.AlakwaaF.AndersenS.JorgensenM.CharlesM.CallaghanB.et al (2021)

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[DOI] [PubMed] [Google Scholar] Salcedo, C

Bioactive compounds in oxidative stress-mediated diseases: targeting the NRF2/ARE signaling pathway and epigenetic regulation