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All the authors approved the final version of the manuscript

However, the intranasal route of drug delivery still has some unresolved issues, such as the need to overcome cilia and mucosal clearance in the vestibular region, as well as enzymatic degradation after the introduction of nanotherapeutic formulations into the nasal cavity[166]

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Its all balanced out with barrier-supporting Lactobacillus ferment and soothing ingredients like panthenol, allantoin, and madecassoside (a cica derivative), which help retain moisture and keep irritation in check

promotes the transportation of calcium to bone], parathyroid hormone (PTH