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Unlike nociceptive or neuropathic pain, pharmacotherapy often yields modest effects and significant adverse effects [46, 396, 397, 398], necessitating a primary focus on nonpharmacological, mechanismbased interventions that target central dysregulation, dysfunctional pain processing, and associated psychosocial comorbidities [46, 264, 398, 399]

doi: 10.1016/j.enzmictec.2005.10.033 374 XiaQ

In the present study, we hypothesized that carnitine deficiency occurs in severely malnourished patients with eating disorders during refeeding and has adverse effects during the course of treatment, such as liver damage, hypoproteinemia, and poor weight gain

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At the same time, we want to minimise the disruption to patients treatment