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108 Moreover, the SPHK1 inhibitor PF543 also effectively relieved ERS by reducing the phosphorylation of eIF2 and activating ATF6, thus remarkably improving AIH

In Supplementary Figures 2C,D, a taurine to vitamin B9 ratio of 1:2,500 demonstrated protective effects on mitochondria against oxidative stress by enhancing their spare capacity (taurine vitamin B9 1:2,500 vs

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