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What is a therapeutic or maintenance dose

While there are no significant adverse interactions between the two, the optimal absorption of each vitamin depends on timing and conditions, such as taking Vitamin D with meals and Vitamin B12 on an empty stomach

Evidence base: Most data comes from preclinical studies and small clinical trials

That said, deficiency is rare and can only be confirmed through a lab test

Serum copper rises naturally during pregnancy as oestrogen drives an increase in ceruloplasmin, the protein that transports copper in the blood, and one 2007 study found that women with a history of postpartum depression had somewhat higher serum copper on average than women without that history