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Neurochem Res

The selectivity profile of 5-amino-1MQ is particularly noteworthy for research applications, as comprehensive enzyme panel screening reveals no inhibition of related SAM-dependent methyltransferases or enzymes in the NAD+ salvage pathway at concentrations up to 10 M

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5-Amino-1MQ 50mg 5-Amino-1MQ (5-amino-1-methylquinolinium) is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT)

By reducing susceptibility to enzymatic degradation, these modifications may potentially increase the peptide's half-life and improve its pharmacokinetics