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Both preventative studies showing reducing UV-induced pigmentation and therapeutic trials demonstrating improvement in melasma and age-associated hyperpigmentation provide evidence for clinical relevance of topical antioxidants [55, 56, 66,67,68]

Human clinical trials conducted over extended observation periods reveal remarkable mortality benefits

Materials and methods Cell culture The cultivation of HCT116 cells was performed via McCoys 5A medium (Pricella, Wuhan, China), and SW480 cells were maintained in high-glucose DMEM medium (Solarbio, Beijing, China), supplemented with 10% serum (HyClone, USA) and 1% penicillin/streptomycin (Solarbio, Beijing, China)

doi: 10.34172/jlms.2021.88

CBD can directly influence various cell types, including neurons and immune cells, by targeting distinct molecular pathways, thereby modulating their functions

see Grimm and Eckert, 2017) and evoke a consequent GSH modulation
