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Although AHCY inhibitors show potential in the treatment of prostate cancer, the safety and side effects of their long-term use remain unclear

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10.1182/blood-2005-06-2506 Blood 88 KangJ

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The micronutrients of methyl donors in the one-carbon metabolism have been reported to be neuroprotective, can cause global or gene-specific changes by epigenetic mechanisms, and could be used in a regulated manner to mitigate the symptoms of neurodegenerative diseases and stress-related disorders at early stages of prognosis

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Downregulated ELC transcripts were enriched in transcripts involved in alternative splicing and transcripts encoding membrane proteins

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