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These adverse effects are probably caused by the drugs themselves rather than by extraneous factors, as indicated by the results consistency across several studies and low degree of heterogeneity

2017;66:A321
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This means the medication might not control blood sugar or help with weight loss as expected

somnifera increases the mRNA expression of lipid metabolism-related genes, including sterol regulatory element-binding protein 1c (SREBP-1c) and cytochrome P450 7A1 (CYP7A1), in the liver of HFD-fed mice (97)

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