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CD73/adenosine pathway involvement in the interaction of non-small cell lung cancer stem cells and bone cells in the pre-metastatic Niche

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Start with tirzepatide monotherapy, titrate to therapeutic dose (12.515mg weekly), allow 1620 weeks to reach plateau, then reassess

First: the lipolytic effect in animal models (in rats and mice on a high-fat diet) did not translate to humans with stabilized obesity

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