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Thus, they suggested that these compounds exert their maximum benefits in healthy individuals or during periods of remission, whereas they may suppress some of the signaling involved in inflammation promotion during active disease stages [376]

PubMed Central PMCID: PMC10719533 Sun X, Ou Z, Chen R, Niu X, Chen D, Kang R et al (2016) Activation of the p62-Keap1-NRF2 Pathway Protects against Ferroptosis in Hepatocellular Carcinoma Cells

Vander Velde R, et al

Autophagy, in turn, could reduce oxidative damage by engulfing and degrading oxidized substances

Results The threshold of mechanical allodynia was significantly increased in the BPC10, BPC20, BPC40 and morphine groups compared with that in the control group at 2 h

Confirmatory GPX1 enzyme-linked immunosorbent assay (ELISA) Kit analysis was then performed, and the results demonstrated that GPX1 expression in the PT group was significantly decreased compared to the sham group, whereas allicin significantly increased the expression level of GPX1 in the infarct area of mice with cerebral infarction, consistent with our proteomic results (Fig