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On the other hand, as a new attempt, from the cytoprotection viewpoint and potential involvement of the cytoprotective agents, we reviewed the potential significance in the heart disturbances of the therapy with the stable gastric pentadecapeptide BPC 157 (for review, see, i.e., [2,3,4,5,6,7,8,9])

Similar to several vitamins, which have specific transporters for their uptake, ET is imported into cells by a specific transporter, the ergothioneine transporter (ETT/SLC22A4), in a sodium- and pH-dependent manner (42, 130)

Two isoforms of these transporters are known, and although similar in amino acid sequence and structure, they have different tissue distributions [20]

Gap junction-mediated transfer of mitochondria, cytokines, and growth factors further enables DTPs to get stromal support [127]

The concentration of malondialdehyde (MDA) was determined by measuring the reaction of thiobarbituric acid with MDA and quantified as nmol/100 mg of tissue

2.1.2 Iron transport in brain Iron is an essential cofactor for many metabolic processes in the central nervous system (CNS), including DNA synthesis in neurons, oxidative phosphorylation, neurotransmitter production and oxygen transport (18, 19)