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Calcium homeostasis dysregulation impacts A aggregation, tau hyperphosphorylation, synaptic damage, neuronal apoptosis, mitochondrial dysfunction, oxidative stress, and neuroinflammation [69,70,71,72,73,74,75]
Histological analysis of adipose tissue from 5-Amino-1MQ-treated animals reveals increased presence of multilocular brown-like adipocytes, increased mitochondrial density, elevated expression of UCP1 and other thermogenic markers, and reduced adipocyte size
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When a neuron is damaged due to B12, B1, or B6 vitamin deficiencies, the neuron no longer fires a signal
