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Firstly, our study further strengthen the evidence of well-designed RCTs of ALC in HE and introduce the view and methodology of evidence-based medicine (EBM) when compared with a previous review included 3 clinical trials reported in 2008.28 Secondly, perhaps more and more investigators from different countries will be interested and highlight the role of ALC and conduct studies with far more important findings, so as to provide another choice drug for HE

Para las cantidades ms elevadas se recomienda dividir la ingesta en varias dosis al da, con ello se evitar eliminar el exceso aportado

doi: 10.1053/j.semnuclmed.2016.07.004 47 SahinEElbogaUKalenderEBasibuyukMDemirHDCelenYZ

Davies P, Watt K, Kelly SM, Clark C, Price NC, McEwan IJ

If tube feeding is needed in the long-term, gastrostomy is recommended [172]
