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The recombinant zoster vaccine (Shingrix) is fully covered under Medicare Part D, and most private insurers fully cover it as well

Despite the presence of some growth factors, platelet-derived preparations were removed from the Prohibited List as studies do not demonstrate any performance enhancement beyond a potential therapeutic effect

4 Patients may also have some GI upset with nausea, vomiting, or diarrhea

But these studies were tiny and had no placebo group

In short: B12 shots are used because they deliver vitamin B12 faster, more reliably, and more efficiently than oral supplements, especially if you have an absorption issue

In 2018, the first study evaluating B12 + methylmalonic acid status in the Spanish vegetarian population was conducted