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Furthermore, we found that inhibitors of the MAPK pathway (PD98059) and the PI3K/ATK pathway (LY294002) effectively neutralized the promotion effect of miR-221 antagomir on proliferation and G1 to S cell cycle transition in DPCs and DSCs, respectively, as demonstrated by CCK-8, EdU, and cell cycle assays (Fig

All interventional groups were similarly treated to the normal group

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A physical approach is a microinjection, which employs a glass micropipette to administer RNP precisely into living cells

The inclusion criteria for the reviewed articles were original studies of primary information or previous reviews, the content and scientific importance of the subject, methodological quality, efficacy and reliability of the information, and publications in Spanish or English

While the results are intriguing, the lack of experimental rigor means we cannot be confident about the specific contribution of BPC-157
