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Additionally, regulatory pathways such as Keap-Nrf2, Beclin-1 (BECN1), and ferritinophagy modulate ferroptosis dynamics, providing promising therapeutic targets

Notably, the impact of ferroptosis in PDAC is modulated by genetic and microenvironmental factors

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As mentioned previously, increased cerebrovascular resistance at rest, whether it be related to aging or disease, is typically a negative change in cerebrovascular function and is a sign of greater flow impedanceultimately leading to reductions in CBF (Claassen et al., 2021)

It helps convert carbohydrates into energy and supports the cardiovascular and nervous systems