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In addition to NADPH oxidase, several other enzymes may contribute to ROS generation, including xanthine oxidase, NO synthase (NOS) and mitochondrial enzymes
P53 activation can sensitize cells to ferroptosis after ROS-induced stress by repressing the expression of GPX4 and system Xc component SLC7A11, which limits GPX4 substrate availability [61, 63,64,65,66]
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Modulating Potential of L-Sulforaphane in the Expression of Cytochrome P450 to Identify Potential Targets for Breast Cancer Chemoprevention and Therapy Using Breast Cell Lines
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