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This finding supports the tandem use of anti-CD38 antibodies and PD-1/PD-L1 checkpoint blockers to enhance the immune response to cancer, thereby providing a two-pronged approach to immunomodulation of the tumor microenvironment

The standard cycle is 8 to 12 weeks on, followed by 4 to 8 weeks off

Referral is also appropriate for severe anaemia, malabsorption disorders, or when the cause of deficiency remains unclear

In rare cases you may suffer bruising, redness, swelling or itching at the injection site which is normally transient and limited to 48 hours

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Hydration: Staying well-hydrated is essential for overall bodily function