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Description
Intl J Biomed Pharma Sci

Pharmaceuticals 15 , 1306 (2022)

437 Targeted exosome Exosomes are extracellular vesicles that adhere to the plasma membrane of various cell types and can be released by almost all cell types

For instance, UCP2 knockout mice exhibit an inverse correlation between mitochondrial ROS production and mitochondrial numbers in dopaminergic neurons

Thus, targeting IRE1 and its associated pathways may represent a therapeutic strategy to reprogram the TME, enhancing the effectiveness of existing immunotherapies

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