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Low-Dose Naltrexone Reduces Pain and Improves Function in Fibromyalgia Low-dose naltrexone (LDN) significantly reduces pain and improves functional outcomes among patients with fibromyalgia while maintaining a favorable safety profile, according to study results presented at the American College of Rheumatology (ACR) Convergence 2025, held from October 24 to 29, in Chicago, IL
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