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10.1016/j.heliyon.2023.e18682 120 KrausV

These IR-induced mitochondrial defects are evident in both insulin-sensitive tissues (liver, muscle) and in the heart and brain, providing a mechanistic link between metabolic dysfunction and cardiovascularcognitive comorbidity

The signaling pathway responsible for these effects appears to be cAMP/PKA/CREB, which in this study was shown to be negatively regulated by both NESF and NLP ( Figure 9 )

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The TRAP assay uses ROO generated from AAPH and peroxidizable materials

[DOI] [PubMed] [Google Scholar] 18.Correction: Vitamin B(12) deficiency