people going blind from glp 1 Do Medications Cause Blindness Breaking Down the Danish Study? Lipsitz, Ponterio & Comerford |
Description
Reduces appetite aids weight loss Common Drugs (Examples) Exenatide Liraglutide Dulaglutide Semaglutide Lixisenatide Clinical Uses Type 2 Diabetes Mellitus (as monotherapy or combination) Obesity / weight management (especially semaglutide, liraglutide) Cardiovascular benefit: reduces major adverse CV events in T2DM with CVD Administration Subcutaneous injection (daily or weekly depending on formulation) Oral semaglutide available for some patients Adverse Effects Gastrointestinal: nausea, vomiting, diarrhea Risk of pancreatitis (rare but serious) Mild hypoglycemia if combined with sulfonylureas or insulin Injection site reactions Contraindications / Precautions Personal/family history of medullary thyroid carcinoma History of multiple endocrine neoplasia syndrome type 2 (MEN2) Severe gastrointestinal disease (gastroparesis) GLP-1 agonists = incretin mimetics

GLP-1 Semaglutide + Cagrilintide studied in appetite and metabolic pathway research models.
Although, in the last 10 years, the use of GLP-1 RAs, especially semaglutide and liraglutide, has increased, its clinical implications and how it affects metabolic parameters have yet to be fully consolidated

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People who stop taking GLP-1 medications like Ozempic and Wegovy started to regain weight in a short amount of time, according to a new study.

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