l-acetyl-carnitine Acetyl-L-carnitine Hydrochloride | 5080-50-2 Acétyl-L-Carnitine
Description
Introduction Chronic heart failure (CHF) is a complex clinical syndrome characterized by decreased myocardial contractility, hemodynamic abnormality, and neuroendocrine activation

Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy

In addition to its role in energy metabolism with some antioxidant properties, L-acetyl-carnitine can cross the blood-brain barrier, where it modulates brain neurotransmitters, such as acetylcholine, serotonin and dopamine, and acts on neurotrophic factors by modifying the activity of the relevant genes

The researchers note that L-carnitine is used as a dietary supplement by some to ward off cognitive decline or improve fat metabolism

L-CARNITINE also assists in the oxidation of pyruvate and branched chain amino acids in the energy cycle, and prevents the buildup of fatty complexes within cells which can damage muscle cell membranes

McAllister, G
