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The cardiovascular benefits, including reductions in MACE and stroke, also accumulate over time, with the most substantial gains observed within the first 24 to 36 months of treatment [124, 125]
Primary Data Analysis To address potential confounding, we extracted adjusted risk estimates when available and noted the covariates included in each study's analysis model(s)
Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jdar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML, Woo V, Hansen O, Holst AG, Pettersson J, Vilsbll T
Metformin treatment for 8 days impacts multiple intestinal parameters in high-fat high-sucrose fed mice